Tragedy strikes the McNamara/Troy family after Julia learns what has caused her ill health. A visitor from Christian's past brings revealing news. Sean finds the price of fame to be more expensive than it's worth.

Homer and Marge enjoy a night out on the town. Meanwhile, at home, the kids deal with a diabolical babysitter.

The decomposed skeleton of a young woman is found in a shopping cart, but due to an aging disease she is reconstructed by Angela as an 80-year-old woman. Booth and Brennan investigate and are led to a former caretaker of the victim, but their lead is shaky and they have trouble finding out who would want to kill such an innocent young woman. Meanwhile, Max Keenan, Brennan's father, reappears with information from her past. Also, Hodgins and Angela walk down the aisle, but everything doesn't go as planned.

Fry downloads Lucy Liu's image from nappster.com onto a blank robot and falls in love with the computerized image that is programmed to love him back. His friends, who are worried about Fry, try to shut down nappster.com, and discover that the company has actually kidnapped real celebrities. They grab Lucy Liu's preserved head and try to escape, but nappster.com send an army of warrior Lucy Liu-bots after them.

Michael and Fiona work to rescue Sam from heroin smugglers, after Kent and Melissa's deal goes sour. Meanwhile, Michael attempts to evade the government agents who assassinated Philip Cowan.

When a heat wave hits Quahog, Peter gets Brian to enter a dog show to win $500 so that the family can get a new air conditioner. When they argue over a trick gone bad, Brian walks out on the family and Peter replaces him with a cat. Brian struggles to assert his civil rights and soon ends up at the pound. Luckily, Peter is able to bail him out by bribing the judge.