Sam, Dean, and Ruby look for Anna who hears the voices of angels. When Ruby seemingly betrays the brothers and leaves with Anna, Sam enlightens Dean on how Ruby saved Sam's life while Dean was in Hell.

Miranda's lover always showers afterwards, as he's a Catholic. Carrie discovers Mr. Big takes his mother to church on Sundays. Samantha falls in love with a perfect man, but he doesn't measure up to her requirements. Charlotte consults a series of soothsayers about whether she will ever get married. Carrie breaks up with Mr. Big.

Michael and Lincoln are left with no choice but to hand Whistler over in exchange to save LJ and Sofia. A familiar face enters Sona while another inmate leaves.

After Steve shows a lack of interest in Stan's job, Stan replaces him with Barry, Steve's malicious friend. Barry frames Steve to eliminate him from the household, but when Steve discovers Barry's weakness, he relies on his CIA skills to save the family. Meanwhile, Roger takes an impressive keg-stand and uses it to become a fraternity brother.

Jace, a blackmailer, with Tempus' diary, finds out about Clark's identity and forces him to steal and do everything more that he wants...and one thing more (by Nigel's suggestion)....to kill Lois, or he kills Martha and Jonathan. Lois tells Clark the only way to save his parents is to freeze her, then she will look like a dead person, and he tells her this can be very dangerous to her life, but, even so, she tells him to freeze her. Superman gives Lois (appearly dead) to Jace and Nigel, then they lock Superman in the same place where his parents ...

Nancy is having one of the worst and busiest days of her life. One of her sons is missing. Shane's graduation and the deal with U-Turn make her feel like she needs to be in two places at once even though she really doesn't feel like being in either of them. Heylia's plan is put into action. Nancy tries to deal with Conrad's kiss, Celia's madness, and Kat's craziness. Everything comes to a head when the deal goes wrong.