The students enjoy spring break on the beach. Cappie and Casey explore their new friendship at a time when Rebecca needs Cappie's attention. Evan looks to move on and escape his feelings and ends up with a familiar person. Rusty returns to school and on his way back he reunites with old friends.

After Flack makes an enormous drug bust, and locks it up at CSI, the drug lords infiltrate the building at gunpoint to get them back. Now the team must resolve the hostage situations, all the while with Mac, Stella, and Hawkes trapped inside.

Bart is given the role of a cooper in the school's medieval festival, while Lisa is the queen. Bart is blamed and expelled when rats come out of large pie that is presented to the queen. Marge looks for a new school for Bart and decides to try out a Catholic school. In his first day at school Bart encounters a tough nun and Father Sean. Bart takes a liking to Father Sean and begins to embrace the Catholic faith, which concerns Homer and Marge. Homer goes to the school with the purpose of taking Bart out of school, only ...

Sarah finds herself in a business transaction with a mysterious business man. Meanwhile, Cromartie closes in on John and Agent Ellison discovers a nemesis at the agency. However, events seem to spin out of control yet again. Will Sarah manage to stop the future war against SkyNet while protecting the life of her son?

onclusion. The boys discover the reason for the global attacks by oversize guinea pigs, but first they have to find their way out of the Andes.