House treats a 16-year-old chess prodigy who gets everyone on the team annoyed with his behavior. Foreman is upset with House because he thinks his boss sabotaged his job interview with another hospital.

Cigarette Smoking Man returns as Mulder investigates the attempted assassination of a young boy with psychic powers who may be the proof that he has looked for all his life. On his way he encounters many enemies especially in the finale' as his office and every X-File is torched by CSM.

Homer and Marge enjoy a night out on the town. Meanwhile, at home, the kids deal with a diabolical babysitter.

Azula attacks the Western Air Temple, forcing the gang to flee. Meanwhile, Katara still doesn't trust Zuko. Zuko talks to Sokka, and confirms that he knows the person who killed Katara's mom. When Zuko and Katara go off to find him, will Katara go too far when she does?

When an unexpected person comes to Mulder's rescue, Mulder refuses to slip north over the border to safety. Instead, he heads southwest to the Anasazi ruins of New Mexico seeking a mysterious wise man whom the Indians call The Keeper of the Truth.