Tom and Diana continue their investigation on Jordan Collier's plan for mankind. Dennis Ryland returns to NTAC. Isabelle is seriously injured when she takes a classroom hostage.

After Will and Grace decide to have a baby together, obstacles pile up before them, including a missing specimen sample and bungled insemination efforts that have them teetering between artificial and natural means – all leading to mis-conceptions. Meanwhile, when Jack considers giving up his show-business aspirations, until he gets some career advice from a "divine" entity – his idol, Cher. Likewise, married Karen is sorely tempted by the romantic tickling of a rich and natty gentleman.

Sarah finds herself in a business transaction with a mysterious business man. Meanwhile, Cromartie closes in on John and Agent Ellison discovers a nemesis at the agency. However, events seem to spin out of control yet again. Will Sarah manage to stop the future war against SkyNet while protecting the life of her son?

The investigation into the rape and impregnation of a young girl with Down's Syndrome uncovers a serial rapist who preys on handicapped young girls under the guise of being their benefactor.

The Task force believes the Bay Harbor Butcher case is closed, but Dexter still has some trouble to deal with.

While Ebisu trains Naruto on how to walk on water in a hot spring, he spies somebody trying to peep on women in a hot spring. Ebisu attacks him, only to be defeated quickly. Since Naruto's teacher has been knocked out, Naruto demands that the stranger become his teacher instead, but he has other plans. Naruto's Sexy Jutsu may be just the thing to get this pervert's attention.