Tragedy strikes the McNamara/Troy family after Julia learns what has caused her ill health. A visitor from Christian's past brings revealing news. Sean finds the price of fame to be more expensive than it's worth.

A surprise guest shows up at a sad event as Bette gets stunning news about her job. Tina goes into a surprisingly difficult labor, Jenny finally reaches breaking point over her painful childhood memory, Alice struggles with her jealousy, and Peggy Peabody lays down the laws with her daughter, Helena.

The battle with Ichigo and Amagai comes to a close. Amagai finds out the shocking truth of his father's death.

After Petrovsky leaves Carrie behind for a second time in Paris, she begins to wonder if she's doomed to follow in Juliet's footsteps. Back in New York, Samantha's chemo treatments are killing her sex drive, and she tries to push Smith away in an attempt to cope with it. Hoping to adopt a baby, Charlotte and Harry host an expectant couple from North Carolina, with the intent of acquiring their unborn child.

Sheppard returns from a mission and finds Atlantis abandoned and surrounded by sand dunes. He soon finds a hologram of Dr. McKay, who tells him he has come 48,000 years into the future, and everyone is long dead. But the McKay hologram has a plan to save the city and restore Sheppard to his own time.

Clark discovers the reason Lana married Lex then and sets out to kill Lionel. Lex tries to use DNA from the last phantom to power his super-soldiers. Lois goes to a dam to search for Lex's lab but is caught by a security guard and fatally injured. Chloe's power is discovered.