Emerson is hired by Dusty Fitz, whose wife Kentucky died in a tragic bee-related incident. She was involved with another man who Dusty claims she was preparing to leave, and Dusty suspects murder. Meanwhile, Lily helps Olive move to a nunnery.

Gabrielle, Susan, and Lynette rush to the hospital in the middle of the night after receiving a phone call from Danielle telling them about Rex's heart attack. Bree confides that she feels guilty because she and Rex were having a fight when he had his heart attack and that now he needs a pacemaker. Before his operation, Rex apologizes for being a bad husband. After not getting any better, the doctor suggests to Rex that maybe Bree was tampering with his medication. Rex writes her a note telling her that he understands, and then dies not knowing the real truth. ...

This is the second hour of a 2-hour season finale. A two episode entries have been created. The 10pm EST marker will mark to beginning of the second episode. A couple undergoes surgery. Derek and Meredith clinical trial has another patient. Izzie helps Alex. McSteamy hooks up with someone.

After a hard day of work, Dr. Cox has the burden to tell his son Jack a good night story, so disguises his hard day as a fairy tale about the little village Sacred Heartlia with Carla and Turk as the two-headed witch Turla, Elliot as the princess and J.D. as the village idiot. Other people featuring are the Janitor as the giant, Keith as the prince, Dr. Kelso as the dark lord Oslek, Ted as his hunchback and of course Dr. Cox as the brave knight.