Lynette and Tom uncover the unsettling truth about son Porter. Gabrielle suspects Carlos' best client, Virginia (guest star Frances Conroy), has ulterior motives. Bree's moment of weakness could bring her great embarrassment and shame. Katherine's not-so-little secret is unveiled. Susan learns of Jackson's true passion. Finally, Mrs. McCluskey's sister Roberta (guest star Lily Tomlin) unearths a disturbing fact about Dave.
Nathan learns of his father's plans, while Flint and Knox launch attacks on Hiro, Ando, Peter, and Claire. Meanwhile, Matt tries to revive Angela, Sylar meets with Elle, and Mohinder begins testing of his newest superpower formula.
It's Thanksgiving time and Blair is offended when her Mom's new man hijacks her Thanksgiving traditions. Lily attempts to fix Jenny and Rufus's frail bond. Eric discovers a secret on Bart.
Brainiac strikes and replaces Chloe's memories with Kryptonian code. In order to help his best friend, Clark must ask for Jor-El's help. Meanwhile, Davis tries to get Chloe to understand that Jimmy is wrong for her.
One of Meredith's oldest friends, Sadie, becomes an intern at Seattle Grace, but Mer's friends are less than welcoming to her. Lexie leads her fellow interns in secretive, unorthodox surgical training sessions; and a new surgeon, Harriet Dixon, brings rules and order to the OR.
Turtle scores a first class seat next to the star of a now finished HBO series, and makes a mile-high claim to the guys; Josh Weinstein courts Vince whilst Ari is distracted.
TESTING THE EFFECT! WAIT UNTIL THE WHOLE PAGE LOADS, THEN CLICK PLAYER TWICE.
Carrie thinks her relationship with Big has evolved enough to the place where she can leave stuff at his place. She purposely leaves a few items on his bathroom, only to be surprised by Big the next morning with a bag with all her items in it. Carrie is confused and tries to discuss it with him, but realizes she doesn’t have to leave her marks on his place to know they’re in a relationship. Meanwhile, Miranda feels her biological clock ticking when her gynecologist tells her one of her ovaries has stopped production. She starts taking hormones and going out on dates with guys she’d never go – like her co-worker with the hair plugs – but a discussion about freezing eggs leads her to realize she’s only 33 and still has one ovary working. Samantha has the chance of getting back to the one guy who broke her heart, but can’t resist the temptation of jumping to bed with him. Her vengeance plan goes down the drain when he dumps her and she realizes she hasn’t evolved past having feelings quite yet. And Charlotte finds a piece of the male evolution of her own: a man who could be either a gay straight or a straight gay. The difference? The gay straight is nothing but the product of overexposure to the high life in Manhattan, but is still straight. Confused, she decides to go forward with the guy, but realizes her male side isn’t as evolved as Stephan’s female side.
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