Michael tries to save his brother and himself from the unstoppable Mahone. Kellerman's testimony at Sara's trial proves different from what was expected. Sucre puts everything on the line to save Maricruz. Just like old times, T-Bag and Bellick are at it again.

The day has finally come for Sara's trial. Michael is determined to stop T-Bag's reign of terror. Bellick is money hungry and will do whatever it takes to hunt down T-Bag. Kellerman decides his fate while Lincoln and Mahone square off.

Sara sacrifices herself for the safety of Michael so the brothers can get on with their final plan to attain freedom, but their plan gets 'shipwrecked'. Meanwhile, Bellick blackmails Sucre to partner up as T-Bag's streak of murder continues to the south of the border.

An unlikely alliance forms between Bellick and Sucre while Michael is determined to face the president. T-Bag gets into some trouble when he loses his luggage. C-Note faces major consequences after some of his actions.

T-Bag digs deep and finds his 'nice-side' with the help of a psychiatrist. Michael, Lincoln, and Sara get their hands on evidence needed to clear Lincoln, while Kellerman is close to finding the President.

Michael and Sara request Henry Pope's help in retrieving the information that could possibly exonerate Lincoln. Mahone pins down an escapee. Sucre discovers a new threat while hitchhiking to reunite with Maricruz. T-Bag brings the Hollander family to his home.

C-Note gets into a tricky situation when a robber holds up the diner he is in. Michael, Lincoln and Kellerman get closer to revealing the conspiracy with the help of Sara. Mahone recruits Bellick.

In Mexico, Sucre gets a car but gets in trouble with the police. Bellick has more trouble as prisoners who suffered under him want revenge.

Bellick gets a taste of the medicine he gave out when he was the captain at Fox River. Agent Mahone's ex-wife makes another appearance, as Mahone is forced to make a difficult decision. Kellerman reveals his motivation for aiding the escape. T-Bag rekindles an old romance.

Bellick is anything but happy about his sudden homecoming-to Fox River. Elsewhere, Michael and Lincoln might face a homecoming of their own. Mahone and Kellerman use everything they have to make certain that Michael and Lincoln do not get through their road trip alive. Sucre's getaway plane encounters some difficulties. T-Bag closes in ...