While on their separate vacations, each member of the BAU receives a clue from a psychopathic killer who challenges them to save his next victim.

The BAU works with the CIA to identify a mole within that organization whose leaks are putting operatives at risk.

The BAU works to capture a serial killer who has evaded capture by altering his appearance.

The BAU travels to Mexico to aid in the capture of a serial killer who has targeted elderly women.

Reid finds himself in danger when he falls for a starlet whose stalker has turned into a killer.

The BAU travels to New York City to investigate a series of murders that appear to have been committed by a vigilante who is exacting revenge on other criminals who have been released by the justice system.

When college students in New Mexico are found tortured and murdered in an unoccupied house, the BAU suspects a group of killers with a knowledge of Native American rituals is responsible.

A serial killer reappears after 20 years of silence and contacts the BAU through Gideon's retired mentor, who had made his life's work tracking the killer, with the promise he will kill another victim in the next five days.

After interviewing a married couple sitting on death row for serial murder, Gideon suspects the woman is actually innocent. But since she's set to be executed in two days, it's a race against time to prove it.

The team travels to New Jersey where several people have been poisoned, one fatally, with LSD 10 times more potent than the street version.