Derek’s confidence is shaken like never before as he faces off with Addison over what course is best for their dying pregnant patient; Cristina calls the abilities of a renown surgeon into question after she botches a standard procedure; and Bailey, who has decided to pursue a fellowship in Pediatrics, is appalled by the Chief’s less-than-stellar recommendation letter.
Part one of a two-hour season finale. Izzie spends time with a fellow cancer patient and contemplates whether or not to undergo a risky surgery, as Mark is ready to take his relationship with Lexie to the next level. A patient makes Owen reassess his place at Seattle Grace and Izzie’s surgery to remove the brain tumor has dire consequences. This is the second hour of a 2-hour season premiere. A two episode entries have been created. The 10pm EST marker will mark to beginning of the second episode.
In the first part of the two hour season finale, Izzie spends time with a fellow cancer patient and contemplates whether or not to undergo a risky surgery, as Mark is ready to take his relationship with Lexie to the next level and a patient makes Owen reassess his place at Seattle Grace. This is the first hour of a 2-hour season premiere. A two episode entries have been created. The 10pm EST marker will mark to beginning of the second episode.
It’s Meredith and Derek’s wedding day, but as the day progresses could another couple end up getting married instead? Izzie is confronted with cancer once again when she meets another cancer patient. (portrayed by Liza Weil) Derek gives Meredith a wedding gift (her first solo surgery).
As preparations continue for Meredith and Derek’s wedding, several residents must face the arrival of their parents at the hospital: Izzie’s mother Robbie causes a stir when she pays a surprise visit, and Thatcher returns to make amends with Meredith and Lexie. The Chief clashes with Meredith over a controversial medical case.
Amidst a series of intense treatments, Izzie throws herself into Derek and Meredith’s wedding plans, but the stress of her illness takes its toll on Alex - who freezes during surgery just as George begins to excel. Meanwhile: Callie’s father arrives at Seattle Grace, but is less than pleased to meet his daughter’s girlfriend; Owen seeks help to quell his PTSD outburtsts.
All eyes are on Derek as he is set to perform his first surgery after his breakdown; attention is also set on Izzie, whose medical condition requires her to undergo a difficult surgery; and Owen has another PTSD episode that injures Cristina and traumatizes both of them, throwing the future of their relationship into question.
After his fellow surgeons try and fail to bring Derek back to work, Meredith must summon the strength to convince him. Meanwhile the hospital is abuzz as Mark attempts a rare face transplant surgery. Cristina, at last awarded her first solo surgery, is more focused on the needs of her friends, and Izzie does her best to keep her medical condition a secret.
After learning at a deposition that more of his patients have died than survived, Derek decides to quit, even as Meredith refuses to give up on him. Meanwhile Bailey and the Chief continue to bicker over her peds fellowship until Adele steps in to mediate. The interns discover something unsettling on a “patient x,” unaware that the charts they’re looking at are actually Izzie’s.
Derek’s confidence is shaken like never before as he faces off with Addison over what course is best for their dying pregnant patient; Cristina calls the abilities of a renown surgeon into question after she botches a standard procedure; and Bailey, who has decided to pursue a fellowship in Pediatrics, is appalled by the Chief’s less-than-stellar recommendation letter.
Addison, Naomi and Sam rush the ailing Archer to Seattle Grace and reunite with old friends Derek and Mark to help save his life; meanwhile, Izzie employs her fellow doctors in a medical game designed to help teach the interns, and Owen runs into a significant someone from his past.
Now that Derek has the engagement ring, he searches for the perfect way to propose to Meredith, as Lexie demands that Mark go public with their relationship, and Bailey, encouraged by her work on recent cases and by Dr. Dixon, considers a new direction for her medical career.
Bailey grows desperate as a patient’s condition becomes more and more dire. Everyone in the hospital is stepping up to try to find the boy a new organ donor, including Meredith, who considers a death row patient’s wish to die before execution. Meanwhile, an injury leaves Mark in a compromising position in the OR and Cristina awkwardly avoids Owen.
Derek’s mother, Carolyn, makes a surprise visit to Seattle and meets Meredith for the first time, as Mark tries to conceal his relationship with Lexie from her as well; meanwhile, death row inmate William wishes to donate his organs to Bailey and Arizona’s patient, as Owen and Cristina try to go on their first date.
Bailey teams with Seattle Grace’s new pediatric surgeon, Dr. Arizona Robbins, to save the life of a young patient near and dear to her heart, as the admittance of a death row inmate at the hospital stirs anger in Derek and further erodes Meredith and Cristina’s friendship; meanwhile, Callie and Sloan work as a team to fight their respective attractions to Sadie and Lexie, and Izzie tells Alex that she’s seeing Denny.
Cristina is awarded the first solo surgery among the residents, but she has to relinquish it and choose her replacement; Mark performs a cutting-edge procedure to restore a patient’s speech, impressing Lexie in the process; and Callie can’t figure out if Sadie (Melissa George) is flirting with her or just being friendly.
Meredith, Cristina and Bailey come to Lexie and Sadie’s rescue when a routine surgery goes horribly wrong, as Owen and Derek treat a man seriously injured while sleepwalking and Mark comforts the sleepwalker’s distraught daughter.
One of Meredith’s oldest friends, Sadie, becomes an intern at Seattle Grace, but Mer’s friends are less than welcoming to her. Lexie leads her fellow interns in secretive, unorthodox surgical training sessions; and a new surgeon, Harriet Dixon, brings rules and order to the OR.
The Chief announces to the residents that a solo surgery will be awarded, and the news sends them into a competitive frenzy. Meanwhile Derek turns to Bailey for advice when he feels Cristina is interfering in his relationship with Meredith, and Erica discovers a shocking connection between one of her surgical residents and a longtime patient.
To help Bailey become the best general surgeon at Seattle Grace, the Chief gives her new power, new responsibility, and the challenge of removing a young girl’s inoperable tumor. The new head of trauma, Owen Hunt, challenges both the attending doctor’s methods and the residents’ surgical abilities.
Bailey heads up a “domino procedure,” in which each surgery hinges on the one preceding it. Meanwhile, Derek gets sole credit for the brain-tumor study he did with Meredith; Lexie tries to get George to notice her romantically; and Sloan counsels a desperate Callie in the ways of love.
Meredith gets upset when Derek finds her mother’s diary; Callie worries about her first “official” date with Erica; and Cristina discovers a part of the hospital that neither she nor her fellow residents had seen before.
A plumbing leak becomes a deluge and wreaks havoc at Seattle Grace, as the Chief attempts to implement new teaching policies and George tries to retake his residency exam. Meanwhile Derek hopes to make some changes at Meredith’s house.
Second hour of the season five preimere, Meredith and Derek discover the morning-after side of their renewed relationship; a military doctor (Kevin McKidd) who arrives at the hospital with a trauma patient catches Cristina’s eye; and the chief learns that Seattle Grace’s national rankings have slipped.
In the two hour fifth-season opener, Meredith and Derek discover the morning-after side of their renewed relationship; a military doctor (Kevin McKidd) who arrives at the hospital with a trauma patient catches Cristina’s eye; and the chief learns that Seattle Grace’s national rankings have slipped.
Summary: Locke tasks Sawyer with a mission, and Kate talks to Locke while holding a fake, plastic gun while Sayid is watching them.
Summary: Members of the sales staff let Sabre’s new Sales Is King policy go to their heads.
Summary: A high school senior repeatedly hallucinates after blacking out during a class trip; Wilson tries to furnish his condo.
Summary: The team reopens the case of a dock worker, who moonlighted as a professional wrestler, who was shot dead in 1986; Valens secretly looks into a lead on the man who mugged and raped his mother.
Summary: Casey carries out a side mission for his old commanding officer James Keller that leads to him committing treason. When Chuck learns the dark truth about Col. Keller, he and Sarah set out to break Casey out of jail and clear his name. Meanwhile, Awesome’s plan to keep Ellie out of danger gets more difficult when she gets her dream fellowship.
Summary: Kitty’s popularity surge creates havoc for her family; Luc faces the possibility of deportation; Nora reaches out to Tommy for help.
Summary: Naomi goes on her first hike with Ivy and Liam; Annie gives Jasper an ultimatum; Gia and Adrianna’s friendship grows.
Summary: Liz keeps running into Wesley (Michael Sheen), causing her to question their decision; Jack tries to secure his position in the new company.
Summary: While Jack and Cole team up in the field to shield New York from the calamitous threat, a hostage situation has CTU completely stressed out. Meanwhile, unrelenting parole officer Prady presses on in his investigation, and unexpected developments send the Hassan family into a major tailspin.
Summary: Rufus and Lily grow suspect of Jenny’s relationship with Damien. Chuck learns more about the woman who may or may not be his mother. Dan and Vanessa struggle through the awkwardness of dating other people.